I was on oxycodone for 10 years as I have had 5 ankle surgeries and also gave a bleeding disorder so taking Aspirin to monitor pain. I came of the oxycodone in November of 2017 and I’ve noticed a few things aside from the initial affects of coming off of an opioid. I am suddenly breaking out a lot, my hair (which has been straight my whole life) is curling, I’ve lost 20lbs without really trying, my temper is short and I’m irritable easily. My wife says I’m making poor judgement calls and that I’m not being rational, she mentioned that she thought my hormones might be off. She has mentioned to me getting them tested along with my thyroid. Is is this a possibility? I know that oxycodone can lower testosterone, is it possible that I’m over perdusing or have some type of hormone imbalance?