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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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I Was Taking Oxycodone For Cycling Injury And Broken Bones. Does Oxycodone Affect Cholesterol ?

I m 6 5 200 lb male 61 years old, very active lifestyle (gym, bicyclist, kayaker, etc.). My doctor has me on naicin to raise my HDL cholesterol. I had a cycling injury with multiple injuries and broken bones, was taking oxycodone for pain at time of my regular bloodwork. My HDL cholesterol actually went down this time instead of up. What s going on here?
Sat, 4 Jun 2011
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General & Family Physician 's  Response
Oxycodone does have a detrimental effect on LDL/HDL ratio.
It increases the LDL levels as well as decreasing HDL levels.

You might be better off getting prescribed an alternative better opioid analgesic, after consulting your doctor.
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I Was Taking Oxycodone For Cycling Injury And Broken Bones. Does Oxycodone Affect Cholesterol ?

Oxycodone does have a detrimental effect on LDL/HDL ratio. It increases the LDL levels as well as decreasing HDL levels. You might be better off getting prescribed an alternative better opioid analgesic, after consulting your doctor.