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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Injured In Calcified Granuloma. Took Eptoin, Lamitor, Lerozep. Trying To Conceive. Will It Affect Baby?

Dr. good morning, my wife had injured in calcified granuloma in left parental region, she get tab such as eptoin100 mg, lamitor dt 50mg, lerozep 0.5mg. she get consult md in spl neuro center from oct 2012 to till date. now she is geting pregnant. is it affect to baby, is it serious, when will stop the medicine?
thank you sir
Thu, 5 Sep 2013
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Psychiatrist 's  Response
thank you for your query. eptoin (phenytoin) is an antiepileptic, which can give rise to congenital malformations in the child, like cleft palate, facial and limb deformities, mental retardation, cardiac problems, lung problems etc. Lamitor (lamotrigine) is another antiepileptic which can also cause congenital malformations (but safer than phenytoin) like cleft lip. lorazep 0.5mg is a benzodiazepine, which can also give rise to harmful effects in the fetus, like decreased respiration, etc. Moreover, a combination of more than one anti epileptic drug is another independent risk factor for harm to the fetus.
If a patient with your complaints comes to me, I would first make a risk assessment about the current frequency of seizure and an approximate estimation of risk of future recurrence. based upon that, if at all I had to give prophylactic (preventive) anti epileptics, I would prefer to give only one relatively safe drug, like lamotrigine or carbamazepine with folic acid in adequate doses, rather than small doses of multiple drugs, thereby increasing the risk.
i would suggest you to contact your treating doctor urgently about your plans for pregnancy and discuss the drugs needed to be taken.
hope i've been able to satisfy your query. please feel free to contact me for further clarifications. best of luck.
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Injured In Calcified Granuloma. Took Eptoin, Lamitor, Lerozep. Trying To Conceive. Will It Affect Baby?

thank you for your query. eptoin (phenytoin) is an antiepileptic, which can give rise to congenital malformations in the child, like cleft palate, facial and limb deformities, mental retardation, cardiac problems, lung problems etc. Lamitor (lamotrigine) is another antiepileptic which can also cause congenital malformations (but safer than phenytoin) like cleft lip. lorazep 0.5mg is a benzodiazepine, which can also give rise to harmful effects in the fetus, like decreased respiration, etc. Moreover, a combination of more than one anti epileptic drug is another independent risk factor for harm to the fetus. If a patient with your complaints comes to me, I would first make a risk assessment about the current frequency of seizure and an approximate estimation of risk of future recurrence. based upon that, if at all I had to give prophylactic (preventive) anti epileptics, I would prefer to give only one relatively safe drug, like lamotrigine or carbamazepine with folic acid in adequate doses, rather than small doses of multiple drugs, thereby increasing the risk. i would suggest you to contact your treating doctor urgently about your plans for pregnancy and discuss the drugs needed to be taken. hope i ve been able to satisfy your query. please feel free to contact me for further clarifications. best of luck.