Hi. Thanks for your query. Noted the history and understood your concerns. You have a straight query. Azithral that is Azithromycin is known to be effective in typhoid and works well. I would advise you further for getting few more tests like blood culture and sensitivity as this will guide for the best effective medications for typhoid in case of your wife. Also give her probiotics, multivitamins for early recovery. Soft bland diet which is easy for her to digest as typhoid basically starts with inflammation of the terminal that is later part of small intestine. Bed rest is important for good recovery. Proper nutritional support helps further. Get the treatment till cured and ask or discuss about the role of Amoxicillin as further course to get the curative dosages.