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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Fenofibrate Safe And Effective In Reducing Triglyceride Levels?

My triglycerides are high (1000) yet my A1C is 6.9 which the doc said Ok, so how can this be as triglycerides related to sugar too? Also, I have been excercising regularly for 3 months before this blood test and do not sit around eating sugar - how can I live on just meat and veggies to lower all this when my uric acid it too high too ( and the red meat can trigger the high uric acid I have (10.9) and Allopurinol makes me lose lots of my hair so I am to take uloric, won t it do the same thing? This Fenofrbrate the doc wants me to take - I am worried about the side effects - I could not take statins before - how will this be better? Also wants me to take 1 gram of Lovaza a day - if it s the same as Omega 3 fish oil, why can t I take it otc? Thank you so much for your expertise and help. YYYY@YYYY
Sat, 14 Jul 2018
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General & Family Physician 's  Response
Hello and welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

By looking into your report, your triglyceride level is extremely high and HbA1c seems to be fine, but can still be reduced further.
Excess of glucose is converted to fats in the body, which would contribute to raise in triglyceride levels. Hence, consumption of less calories and complex carbohydrates along with exercise should help in bringing down triglyceride level.
Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood by activating the metabolic pathways in cells, which would utilise triglycerides.
Consumption of meat and alcohol would increase your uric acid level. Hence, you need to avoid them to keep your uric acid under normal levels. This would help you to reduce the dose of Allopurinol.
Commonly reported side effects of fenofibrate include: increased serum aspartate aminotransferase and increased serum alanine aminotransferase due to hepatic dysfunction. However, it can be countered by taking appropriate dose and regular liver enzyme monitoring once in 3 months.
Statins block the enzyme in the liver that is responsible for making cholesterol and hence, lowers the level of cholesterol in the blood.
Consumption of Omega-3-fatty acids would be helpful and you can start its consumption after a month or so.
Kindly take the medications and do the necessary follow-up as advised. Gradually, you should see improvement and get better.

Hope I have answered your query. Let me know if I can assist you further.
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Is Fenofibrate Safe And Effective In Reducing Triglyceride Levels?

Hello and welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. By looking into your report, your triglyceride level is extremely high and HbA1c seems to be fine, but can still be reduced further. Excess of glucose is converted to fats in the body, which would contribute to raise in triglyceride levels. Hence, consumption of less calories and complex carbohydrates along with exercise should help in bringing down triglyceride level. Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood by activating the metabolic pathways in cells, which would utilise triglycerides. Consumption of meat and alcohol would increase your uric acid level. Hence, you need to avoid them to keep your uric acid under normal levels. This would help you to reduce the dose of Allopurinol. Commonly reported side effects of fenofibrate include: increased serum aspartate aminotransferase and increased serum alanine aminotransferase due to hepatic dysfunction. However, it can be countered by taking appropriate dose and regular liver enzyme monitoring once in 3 months. Statins block the enzyme in the liver that is responsible for making cholesterol and hence, lowers the level of cholesterol in the blood. Consumption of Omega-3-fatty acids would be helpful and you can start its consumption after a month or so. Kindly take the medications and do the necessary follow-up as advised. Gradually, you should see improvement and get better. Hope I have answered your query. Let me know if I can assist you further.