Hi I had gone through your query. Libotryp contains amitriptiline and chlordizapoxide. Amitriptiline is choice is tension type headache associated with migraine. It prevent further episodes of migraine but can not help to reduce acute migraine attack. Chlordizapoxide is benzodiazapine and help in insomnia. It is safe and useful to treat migraine and insomnia. Still have query then feel free to ask. Happy to help you further. Wish you a very good health. Combination is ideal for headache with sleep problems. You can take it with other drugs that you have mentioned.