Hello dear I understand your concern Mobic and advil should be used carefully under observation of doctor as it increase anti coagulation so high risk of bleeding and bruising. Take following advises: Drug Tramadol, duloxentine Cognitive behavioral therapy Avoid negative self talk and behavior Be creative and learn new things Spends more time with family and friends. Start exercise: Play mind games and walking and swimming Acupuncture therapy Regular yoga Relaxation therapy: whole body massage and breathing technique in fresh air. Bath in salted water Take more Green leafy vegetables, milk, meat, chicken that high in magnesium Diet rich in omega three fatty acid: egg, salmon fish, flaxseed oil Hope this may help you Contact HCM for further health query Best regards Dr. Sagar