Is it common to have an allergic reaction to a one time of an OTC laxative? I recently had a severe and painful sickness that lasted 2 full days of severe lower abdominal cramping and severe stomach pain, violent vomiting. Pain was a 10, cramping was like labor contractions at their worst. I still haven't had a normal bowel movement for 10 days. I have a condition currently with bladder transvaginal mesh erosion. Is it possible there could be a blockage? What should I do next?