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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Normal To Have High ESR And CRP Rates In People With Metastatic Breast Cancer?

I am a 52 y/o female with metastatic breast cancer. My mets are in my bones and liver. My ESR and CrP are high; ESR 130, CrP 7.4. I am almost 3 years post Stage IV diagnosis. Is the ERS and CrP always going to be high because of my cancer? Or do I actually have inflammation somewhere?
Thu, 27 Oct 2016
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Oncologist,  's  Response
The ESR and CrP are both tests that detect inflammation and can be elevated from an upper respiratory infection to cancer. If you have an active stage IV cancer then it is possible for you to have an elevation of this marker (this does not rule out other causes such as infection or autoimmune diseases). Other symptoms such as a fever, joint pain, joint swelling have to be assessed.

As long as you have an active cancer, this markers can be elevated but are not a tool that correlates to cancer activity (Having them elevated does not mean that the disease is getting worse). Other causes may have to be ruled out.
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Is It Normal To Have High ESR And CRP Rates In People With Metastatic Breast Cancer?

The ESR and CrP are both tests that detect inflammation and can be elevated from an upper respiratory infection to cancer. If you have an active stage IV cancer then it is possible for you to have an elevation of this marker (this does not rule out other causes such as infection or autoimmune diseases). Other symptoms such as a fever, joint pain, joint swelling have to be assessed. As long as you have an active cancer, this markers can be elevated but are not a tool that correlates to cancer activity (Having them elevated does not mean that the disease is getting worse). Other causes may have to be ruled out.