Is it safe to start taking Doxycycline a day after taking Azithromycin? I took Azithromycin to treat Chlamydia back in April, but retested positive. My partner is totally against antibiotics, but is willing to take Azithromycin again, since it s only 2 pills and not 2 pills for 7 days. I was wondering if I could take Doxycycline the day after taking Azithromycin with my partner, to make sure the Chlamydia gets cleared so he we don t have to be treated a third time, and to avoid any future discussions with my partner?