Hi, thanks for writing to HCM. There is no relationship between arthritis and leg cramps. And Evista (Raloxifene) is indicated for the treatment of postmenopausal osteoporosis. There are numerous causes for leg cramps (nocturnal cramps). In general, night leg cramps are likely to be related to muscle fatigue and nerve problems. In rare situations, night leg cramps can be associated with an underlying disorder, such as peripheral artery disease — in which narrowed arteries reduce blood flow to your limbs — diabetes or spinal stenosis. Most of the time, night leg cramps occur for no known reason, and they re usually harmless. Activities that might help prevent leg cramps include: • Drinking plenty of fluids to avoid dehydration • Stretching your leg muscles or riding a stationary bicycle for a few minutes before you go to bed • Massaging the cramped muscle with your hands or with ice • Walking or jiggling the leg • Taking a hot shower or warm bath • These cramps at times may be associated with POTASSIUM deficiency and so foods such as bananas, potatoes, prune juice and dried fruit are to be taken as dietary supplement. • Also, calcium fortified foods like seafood and fish, almonds, flaxseed, oats, prunes, sesame seeds, tofu and kale can help to stave off muscle pain & spasm. • Avoid acidic foods and drinks like tomatoes and vinegar which blocks the body’s natural ability to absorb calcium leading to muscle aches & muscle fatigue. I suggest you to consult a Neurophysician for a detailed workup and further management. Hope this information is helpful. Good day