Dear Sir/ madam Thanks for your query. 1. Zocor and Plavix are commonly used drugs for patients of heart attack. Zocor is given almost life long in the absence of contraindications. 2. Plavix is mandatory for first year after stent implantation and can be stopped after one year if your cardiologist advises so. it should not be stopped without cardiologists advise. 3. These drugs may cause some itching but it usually starts early after their commencement and not after many years. you should consult a dermatologist before taking any further action. Feel free to discuss further. Sincerely Sukhvinder