Hello, Paracetamol is a common pain reliever used to treat mild to moderate pain and fever. Warfarin is a blood thinner medication used to prevent blood clots. It is generally safe to take paracetamol with warfarin. Paracetamol is not known to interact with warfarin, so it is not likely to affect the anticoagulant (blood-thinning) effects of warfarin. However, it is important to always consult with your doctor or pharmacist before taking any medications, especially if you are taking other medications or have underlying medical conditions. It is also important to be aware that excessive use of paracetamol can cause liver damage, and warfarin can increase the risk of bleeding. Therefore, it is important to follow the recommended dosages for both medications and to inform your healthcare provider if you experience any unusual symptoms while taking these medications together. In nutshell taking paracetamol in moderate dose as you already mention with warfarin is usually safe with observation. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Shah Hussain, General & Family Physician