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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Use Rutoside As Prostaglandin Inhibitor?

is there any documentation in support of rutoside trihydrate,trypsin & bromaline combination for its usage in nephro patients,specially with regards to safety usage of rutoside as prostaglandin inhibitor. resp. sir i am a medical rep. & i cant pay for your answers/reply, but still look forward to an answer.
Tue, 17 Dec 2019
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General & Family Physician,  's  Response
Hi,

I appreciate your concerns regarding the safety of rutoside in patients with kidney diseases. Prostaglandins play an important role in the normal blood supply within the kidney tissues which contribute to the normal function of the kidneys. Non steroidal anti inflammatory drugs (NSAIDs) such as Ibuprofen or Diclofenac act by reducing the prostaglandins formation in the kidney resulting in kidney damage (nephrotoxicity).

Although rutoside is a naturally occuring flavonoid claimed to be effective in reducing pain and swelling associated with inflammation and since it appears to act by inhibiting prostaglandins formation hence its safety in patients with kidney disease has not been proved on any clinical studies.


Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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Is It Safe To Use Rutoside As Prostaglandin Inhibitor?

Hi, I appreciate your concerns regarding the safety of rutoside in patients with kidney diseases. Prostaglandins play an important role in the normal blood supply within the kidney tissues which contribute to the normal function of the kidneys. Non steroidal anti inflammatory drugs (NSAIDs) such as Ibuprofen or Diclofenac act by reducing the prostaglandins formation in the kidney resulting in kidney damage (nephrotoxicity). Although rutoside is a naturally occuring flavonoid claimed to be effective in reducing pain and swelling associated with inflammation and since it appears to act by inhibiting prostaglandins formation hence its safety in patients with kidney disease has not been proved on any clinical studies. Regards, Dr. Mohammed Taher Ali, General & Family Physician