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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Non Obstructive Azoospermia Curable?

Hello Doctor

This is Mohit here. I am suffering from Non-obstructive Azoospermia (Sertoli Cell only Syndrome), Germ Cell Hypoplasia. I wish if it would be curable with your advice and guidance. I have undergone FNAC twice. First, few years back, and the result were "Maturation Arrest" and second has been done now and the result is "SCO, Germ Cell Hypoplasia". Please suggest if it is curable. Currently my attending doctor suggested that it is not curable. Other details are:Here is the outcome of reports

LH: 9.8
FSH: 16.7
Testosterone: 192
FNAC:
-Specimen: Bilateral Testis
-Gross: Thread Like
-Microscopic Exam: FNA smears from both testis predominantly show clusters as well as single scattered sertoli cells. In addition, right side shows few germ cells with occasional spermatid
The features are of germ cell hypoplasia.

Please suggest if it is curable or not. If yes, kindly suggest how should we proceed and where can we consult to get the desired result.

-Regards
Mohit
YYYY@YYYY
Fri, 15 May 2020
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OB & GYN Specialist 's  Response
Hi,

Unfortunately it's NOT curable. However, there is 30-40% chance of having sperms from the testicles if we do TESE testicular sperm extraction) by which we make small cut in the testes under anaesthesia and see under the microscope. These sperms can be used for ICSI (intracytoplasmic sperm injection) during which the sperms are injected inside the wife's eggs (collected after stimulating the ovaries by injections). The embryo is then transferred inside her womb. In this way, you can become the biological father of your baby.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Sujoy Dasgupta, OB & GYN Specialist
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Is Non Obstructive Azoospermia Curable?

Hi, Unfortunately it s NOT curable. However, there is 30-40% chance of having sperms from the testicles if we do TESE testicular sperm extraction) by which we make small cut in the testes under anaesthesia and see under the microscope. These sperms can be used for ICSI (intracytoplasmic sperm injection) during which the sperms are injected inside the wife s eggs (collected after stimulating the ovaries by injections). The embryo is then transferred inside her womb. In this way, you can become the biological father of your baby. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Sujoy Dasgupta, OB & GYN Specialist