Hi dear and thanks for your query. I understand your concern I will try to help you . Don t worry because Mg haven t interaction with VIt B6 . Side effects from the use of Mg are some but there aren t serious . More common known side effects are : severe stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes or skin (jaundice), dark urine, unusual muscle pain, tenderness, or. weakness especially if accompanied by fever or flu-like symptoms. While common side effects of B6: nausea, vomiting, stomach pain, loss of appetite, headache, tingling, sleepiness Dosage you use is enough and do not use more than 3 months in row. If you will have any side effects I have mentioned above call a doctor. All the best