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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Itching, Elevated Bilirubin, Dark Urine, Breathlessness, Sweating. Prescribed Antihistamine

i have itching, elevated bilirubin , dark urine, light stool, sweaty, short of breath but no jaundice . My glucose is normal, I have no allergies, no hives , no rash, no bites. I went to primary care and they gave me a prescription antihistamine, even though i was adament that i did not think this is an allergy. I am still itchy
Mon, 19 Nov 2012
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Allergist and Immunologist 's  Response
Hello,
Itching with elevated bilirubin may suggest that there is an obstruction in bile flow that most commonly occurs with gall bladder pathologies, and is usually gall stones.
A detailed liver function test (LFT) would have helped to secure this diagnosis if the alkaline phosphatase was also raised.
But as you mentioned no obvious jaundice, it is important to know that the other LFT parameters such as the enzymes are normal.
An ultrasound liver/GB is important at this stage.
Antihistamine will lower the itch but if this liver/GB related itch you will need medications like cholestyramine that should be prescribed after a visit/consultation with a gastroenterologist.
Thanks.
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Itching, Elevated Bilirubin, Dark Urine, Breathlessness, Sweating. Prescribed Antihistamine

Hello, Itching with elevated bilirubin may suggest that there is an obstruction in bile flow that most commonly occurs with gall bladder pathologies, and is usually gall stones. A detailed liver function test (LFT) would have helped to secure this diagnosis if the alkaline phosphatase was also raised. But as you mentioned no obvious jaundice, it is important to know that the other LFT parameters such as the enzymes are normal. An ultrasound liver/GB is important at this stage. Antihistamine will lower the itch but if this liver/GB related itch you will need medications like cholestyramine that should be prescribed after a visit/consultation with a gastroenterologist. Thanks.