I've Had RLS For Several Years (40) And This Year

I've had RLS for several years (40) and this year switched from clonazepam to pramipexole/mirapex (.25mg). My RLS seems to be worse lately so I didn't take it last night. Instead took a regular aspirin along with a clonazepam (.5mg). This seemed to have worked better. Is it possible that I'm actually having an adverse reaction to the pramipexole?? For a larger picture of my condition: I had massive radiation treatment for rectal/colon cancer in 2006, started having leg aches, back problems and just got tired of moving. It came down to scarring and blockage to both legs. This past December I had "Aortic bifemerol bypass" surgery done and am now starting to feel human again and can walk without pain or becoming tired.