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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Medical Examination Showed High Sgpt Levels. Prescribed Godex DS. Ultrasound Showed Moderate To Severe Fatty Liver. What To Do?

my husband underwent medical examination for employment abroad. it was found out that he had high sgpt levels that reached to 156. he was given Godex DS for one month. After taking the prescribed medicine for a week, he underwent again sgpt test which showed that it has reached to 159 though he had changed his diet and had his exercise daily already. he was advised then for an ultrasound and the ultrasound results showed that he had moderate to severe fatty liver and that his gall bladder is contracted. As of this time, no feedback yet from the doctor but he is still continuing to take Godex DS 3x a day. What is now the best thing to do?
Fri, 28 Jun 2013
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General & Family Physician,  's  Response
Hello,
Serum glutamic-pyruvic transaminase (SGPT) is an enzyme helps in the synthesis of amino acid and the breakdown of non essential amino acid in to essential amino acids – helps Nitrogen metabolism - urea formation and Glucogenesis. When there is liver damage the enzymes escapes in to the blood stream. Damage of any muscle, Heart muscle, gall bladder and Bile duct may produce increased levels of this enzyme.
.
Your husband is having Fatty liver and Gall bladder fullness as obvious causes for increased SGPT level. The following is only for your information (Sometime severe exercise can also increase the level. Even though the SGPT is more specific for Liver damage other enzyme levels have to to be assessed)
Medicines + diet + abstinence from alcohol + fat free, carbohydrate rich balanced diet + avoiding hepato toxic drugs + patience will bring down the SGPT level. You can continue Godex DS, along with some more specic drugs like Ursocol, Hepamerz, Heptral etc., as per medical gastro enterologist's advise
Best wishes

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General & Family Physician,  Dr. Hardik Shah's  Response
Greetings,

First,I would like to advise you to get done SGOT,GGT,ALPO4,Serum Protein Level,Prothrombin Time,Lipid Profile,Blood Sugar Level & HBsAg & Anti HCV Ab.
Second Stop Alcohol & Smoking,Stop Fatty/Oily food,Avoid strenous exercise.

Few history details needed are-
Is he having history of any illnessin past-Jaundice/Hepatitis?
Is he taking any medicines/steroids etc....
Is he had any family history related to his disease.
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Medical Examination Showed High Sgpt Levels. Prescribed Godex DS. Ultrasound Showed Moderate To Severe Fatty Liver. What To Do?

Hello, Serum glutamic-pyruvic transaminase (SGPT) is an enzyme helps in the synthesis of amino acid and the breakdown of non essential amino acid in to essential amino acids – helps Nitrogen metabolism - urea formation and Glucogenesis. When there is liver damage the enzymes escapes in to the blood stream. Damage of any muscle, Heart muscle, gall bladder and Bile duct may produce increased levels of this enzyme. . Your husband is having Fatty liver and Gall bladder fullness as obvious causes for increased SGPT level. The following is only for your information (Sometime severe exercise can also increase the level. Even though the SGPT is more specific for Liver damage other enzyme levels have to to be assessed) Medicines + diet + abstinence from alcohol + fat free, carbohydrate rich balanced diet + avoiding hepato toxic drugs + patience will bring down the SGPT level. You can continue Godex DS, along with some more specic drugs like Ursocol, Hepamerz, Heptral etc., as per medical gastro enterologist s advise Best wishes