My 33 year old daughter, about 180 pounds, sometimes has chronic migraines which are treated with toradol injections, which she does at home. For the second time the toradol has not worked. When she gets it fresh from the pharmacy it is consistently effective. If it is stored for any period of time, it does not seem work. I know that the shelf life of liquids is not the same as it is for pills. Could it be that the toradol loses effectiveness when stored in liquid form, even though it is used prior to the expiration date?