My Husband Has Been Experiencing Frequent Nosebleeds. Nostril Has Been

My husband has been experiencing frequent nosebleeds. Nostril has been cauterized several times and packing inserted. He has been prescribed Percocet taken every 6 hrs and an antibiotic. Started last Monday and still taking meds. And packing still in until Wed. June 1st. He also has been told to use Miralax. He has not had a bowel movement in 6 days and he is having discomfort in the legs. He has been eating less, and sitting or lying down more. He has very little energy, too. Should we be concerned?