My wife Has been drinking 2-3 Red Bull's a day for a few years now. She will have one in the morning with no food just her Meds. She has recenently started seeing a pain management Dr. So now she adding those medicines to the Frey. In the last couple month she has been loosing weight like 20-25 lbs. her doc thinks she has an ulcer but I'm sure she wasn't clear on all the issues. Her diet sucks to begin with. Common sense tells me the mixture with a poor diet could cause it. To add more to it she has almost doubled her smoking in the past few months as well