Hello! Thank you for asking on HCM! Coming to this point (facing your actual complains and overall clinical scanario), I strongly recommend you to consult immediately the nearest ER service in your living area, as those cocktails (MDMA, weed, alcohol, etc) are very dangerous for your health, especially for your heart. They may exacerbate form mild blood pressure fluctuations, t oserious arrhythmias, sudden heart attack, and even cardiac arrest and death. So, do not lose any more time, but ask medical help, to undergo a careful physical exam, resting ECG, several lab tests (like complete blood count, CK-MB, troponin, AST & ALT, renal function tests, blood electrolytes, etc), and rule out serious health conditions, as well as start an appropriate therapy for your health status. I strongly recommend you to avoid having such dangerous substances in the future, to protect your health and life. Hope to have been helpful! Greetings! Dr. Iliri