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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Pregnant After Having Had A Kidney Transplant With Abnormal Creatinine Level. Premature Baby Had Heart Failure. Suggest Possibilities?

Hi, Im second pregnant after a kidney transplant in 2001, my mom donored me a kidney and im blessed to have a great health since then. my creatine 1.2-2.0 .. the thing im worry about is.. my firsy child was born 3 months premature with a heart failure and had to have a heart chest surgery after his birth, he is doing well now but im worry abotu my second child and my kidney,, my med. are:: sandimun neoral and azathioprin,, now, he re in USA they said azathiprin is bad for a baby so i have to stop takin it,, in Germany where im origin from they have a different ideas about that and i had to take azathiprin with my first pregnancy back then, wanna know what is right .. thanks
Thu, 28 Nov 2013
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Nephrologist,  's  Response
Hi
Thanks for your query.
Unfortunately there is no consensus about the use of azathioprine in pregnancy. It is generally considered as the safer immunosuppressants but has been known to cause problems.
So we really have to decide between the risks to the kidney versus risks to the baby.
I personally would continue it. However the ultimate decision is between you and your obstetrician and nephrologist.
Hope this helps
Good luck
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Pregnant After Having Had A Kidney Transplant With Abnormal Creatinine Level. Premature Baby Had Heart Failure. Suggest Possibilities?

Hi Thanks for your query. Unfortunately there is no consensus about the use of azathioprine in pregnancy. It is generally considered as the safer immunosuppressants but has been known to cause problems. So we really have to decide between the risks to the kidney versus risks to the baby. I personally would continue it. However the ultimate decision is between you and your obstetrician and nephrologist. Hope this helps Good luck