Hi, There is no sufficient evidence to say that Meclozine causes congenital anomalies in the fetus. In fact, certain studies have showed better outcome when the drug has been used. So, you may continue with the drug, if you wish to, after a discussion with your doctor. The drug can also be taken early in the morning before rising from the bed with beneficial effects. You may also make slight modifications to your diet and include dry fruits like dates and pista to help you control nausea further. This way you can reduce the use of the drug. Reducing anxiety also goes a long way in helping to reduce early pregnancy vomiting. Wish you good health.