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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Prostrate Cancer. BHP PSA, Gleason Score Done. Removal Of Prostrate Required?

my partner diagnosed with prostate cancer . We in position of making up minds which treatment to choose. BHP PSA is 4.23, gleason score 3+3, no perineural invasion, no lymphatic invasion, no invasion into fat, right side prostate 4 cores positve for cancer of 6 submitted, left side prostate 3 cores positive of 6 submitted. Age, just turned 60, no history of this in family, active sex life currently, have macroscopic results if you require then. Removal of prostate now seems rather radical, what would you recommend?
Fri, 27 Sep 2013
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Oncologist, Surgical,  's  Response
One thing that you have not mentioned is whether you have gotten a CT scan or MRI of the abdomen and a bone scan. The MRI/CT will tell us whether the disease has spread out of the prostate or not and the bone scan will tell us if it has spread to the bones.A chest x-ray should also have been done to rule out spread to the lungs. If the disease is confined to the prostate and has not spread anywhere then a removal of the prostate by a cancer surgeon is advisable as the chances of cure with this surgery near 90%. However, that will put an end to his sex life as you already know. If he is absolutely adamant not to undergo surgery, then the only option available is radiotherapy plus hormone therapy. These have their own set of side effects and may decrease the libido. However, it will not make him irreversibly impotent. The downside is that the cure rates will fall and there is a chance that the disease may actually progress and spread to other organs. So, in a nutshell i will advise you to motivate him for the surgery else he runs the risk of putting an early end to his life. In case the disease has already spread to other organs, then the only option is hormone therapy.
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Prostrate Cancer. BHP PSA, Gleason Score Done. Removal Of Prostrate Required?

One thing that you have not mentioned is whether you have gotten a CT scan or MRI of the abdomen and a bone scan. The MRI/CT will tell us whether the disease has spread out of the prostate or not and the bone scan will tell us if it has spread to the bones.A chest x-ray should also have been done to rule out spread to the lungs. If the disease is confined to the prostate and has not spread anywhere then a removal of the prostate by a cancer surgeon is advisable as the chances of cure with this surgery near 90%. However, that will put an end to his sex life as you already know. If he is absolutely adamant not to undergo surgery, then the only option available is radiotherapy plus hormone therapy. These have their own set of side effects and may decrease the libido. However, it will not make him irreversibly impotent. The downside is that the cure rates will fall and there is a chance that the disease may actually progress and spread to other organs. So, in a nutshell i will advise you to motivate him for the surgery else he runs the risk of putting an early end to his life. In case the disease has already spread to other organs, then the only option is hormone therapy.