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Reports Show Suggestive Of Bilateral Spermatocytic Arrest. What Does It Mean ?
I am AAAAA, age34, 9years since marrige under tretment FSH 11.9, hormone (LH)8.20,testosterone 5.40,
histopathology report is (A) Right side, (B) Left side
(A) Right side: Recieved single yellowish bit of tissue measuring 0.3cms all tissue processed.
(B) Left side: Recieved two yellowish bits together measuring 0.2cms. All tissue processed
(A)& (B) Sections from the testicular biopsy studied reveal adequate semineferous tubular lined by spermatogonia ,,primary and secondary spermatocytes. Sections from (B) shows only one tubule showing very occasional spermatids . Rest of the tubular in (A&B) show no spermatids/sperms. Interstitial tissue show small nests of leydig cells.
There is no evidence of malegnacy.
(A)&(B) Features are suggestive of bilateral spermatocytic arrest
Kindly reply to the same.
histopathology report is (A) Right side, (B) Left side
(A) Right side: Recieved single yellowish bit of tissue measuring 0.3cms all tissue processed.
(B) Left side: Recieved two yellowish bits together measuring 0.2cms. All tissue processed
(A)& (B) Sections from the testicular biopsy studied reveal adequate semineferous tubular lined by spermatogonia ,,primary and secondary spermatocytes. Sections from (B) shows only one tubule showing very occasional spermatids . Rest of the tubular in (A&B) show no spermatids/sperms. Interstitial tissue show small nests of leydig cells.
There is no evidence of malegnacy.
(A)&(B) Features are suggestive of bilateral spermatocytic arrest
Kindly reply to the same.
Mon, 1 Jul 2013
Hi,
Thanks for writing in.
From your report, it is inferred that there is no further progression for the spermatocyte stage in the seminiferous tubule. This means the growth of the immature spermatocyte is arrested or stopped further.
There are many rearons for this to occur:
1. Primary arrest: due to genetic cause.
2. Secondary arrest: due to underlying medical conditions like exposure to toxic substances (radiotherapy, chemotherapy, antibiotics), heat or general diseases (liver or kidney insufficiency, sickle cell anaemia).
Hoe this helps.
Thanks for writing in.
From your report, it is inferred that there is no further progression for the spermatocyte stage in the seminiferous tubule. This means the growth of the immature spermatocyte is arrested or stopped further.
There are many rearons for this to occur:
1. Primary arrest: due to genetic cause.
2. Secondary arrest: due to underlying medical conditions like exposure to toxic substances (radiotherapy, chemotherapy, antibiotics), heat or general diseases (liver or kidney insufficiency, sickle cell anaemia).
Hoe this helps.
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