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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Should I Be Concerned About High AST And GGT Levels?

On a life insurance exam, I had AST of 53, ALT of 82 and GGT of 154. I do drink alcohol, but had a ultrasound in 2008 because of high enzymes. Everything was normal. I have been taking Milk Thistle for the past few months in order to get levels down. I have not re-tested. I also take 20 mgs of Lexapro a day.
Please give me your opinion of these numbers. Should I be alarmed? After the 2008 scare, it really makes me nervous to be tested. Probably wouldn't have if not for the life insurance exam. They did approve me on a standard rating.

Thanks so much
Fri, 12 Sep 2014
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General & Family Physician 's  Response
Hello,
Yes alcohol consumption can cause these altered Alt/ Ast levels and more specifically GGT levels, if you had similar elevations in the past and was on Silymarin ( Milk thistle), and your present examination still shows elevated levels , yes you need to be completely examined and tested, you have to first abstain from alcohol, check your liver, get an ultrasound done , so that the baseline Liver status can be known , depending upon your test results you please consult your doctor so that further treatment plans can be discussed. Hope I could help you.
Thank you.
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Should I Be Concerned About High AST And GGT Levels?

Hello, Yes alcohol consumption can cause these altered Alt/ Ast levels and more specifically GGT levels, if you had similar elevations in the past and was on Silymarin ( Milk thistle), and your present examination still shows elevated levels , yes you need to be completely examined and tested, you have to first abstain from alcohol, check your liver, get an ultrasound done , so that the baseline Liver status can be known , depending upon your test results you please consult your doctor so that further treatment plans can be discussed. Hope I could help you. Thank you.