I have just started taking Midrin for my migraines. This past Sunday I had a migraine and took the total of 5 Midrin capsules for my migraine with an ice pack, with no relief, I came in to work on Monday, feeling just a little better. I again took the total of 5 capsules of Midrin and finally went home at 2:00 and finally felt better. I do feel that the fluorescent lights and computer screen were having an affect on my migraine. My question is, is there a time period that I need to give the Midrin before it builds up in my system and starts working?