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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Hip Joint TB. Taking Ethambutol, INH, Pyrazinamide. What Does ESR, RBC And HB Level Indicate?

My father is sufferring for Hip Joint TB. he is 62 yrs old. He is taking anti tb medicine from 31.7.2013. from 31st July to 5th october 2013 he took medicine like Rimstar 4fdc 5 tabs every day (Ethambutol HCI 275mg, INH 75mg, Pyrazinamide 400mg,Rifampicin 150mg) X 5 every day. on the first week of october his blood pressure become to high 210/110. We consult with doctor , docotor advice some medicie to reduce blood pressure , and ask to take rimactazid 300 2 tablet daily (INH 150mg, Rifampicin 300mg X 2)and ask for creatinine test and it becomes 2.7, after 3 weeks we do again creatinine test it becomes 3.1, ESR 115, RBC 6-8. his HB is 8, he does have diabetics. please give me some advice why till now esr is high, hb is reducing and creatinine is become increasing.
Fri, 15 Nov 2013
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Orthopaedic Surgeon, Joint Replacement 's  Response
Hi, thanks for writing to HCM.

Generally, High ESR indicates high level of disease activity (in case of tuberculosis) or some sort of either Infection/ Inflammation in the body. There are numerous causes for an elevated ESR and a detailed clinical examination is necessary to establish the correct cause.

High levels of Serum creatinine indicates compromised renal (kidney) function. It might be due to the Diabetes (diabetic nephropathy) by itself or due to the side effects of some drugs. Consultation with a Nephrologist is necessary for proper diagnosis and further management.

Hope this information is helpful. Good day
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Suffering From Hip Joint TB. Taking Ethambutol, INH, Pyrazinamide. What Does ESR, RBC And HB Level Indicate?

Hi, thanks for writing to HCM. Generally, High ESR indicates high level of disease activity (in case of tuberculosis) or some sort of either Infection/ Inflammation in the body. There are numerous causes for an elevated ESR and a detailed clinical examination is necessary to establish the correct cause. High levels of Serum creatinine indicates compromised renal (kidney) function. It might be due to the Diabetes (diabetic nephropathy) by itself or due to the side effects of some drugs. Consultation with a Nephrologist is necessary for proper diagnosis and further management. Hope this information is helpful. Good day