First my questions to you; did you have basline ivestigations with you;I mean before starting ATT what was the level that will indicate exact rise of your brothers LFT's. If they were normal then yes; they are in high range that too for 10 days of ATT; you cannot continue with same regimen of ATT.

hello, your brother is in the intensive phase of the ATT and is currently taking four different drugs. This SGPT/SGOT result which are about 3x the normal value suggest that he has developed hepatotoxicity which is a side effect of this drugs in the following other INH + rifampin > INH alone >> pyrazinamide alone > rifampin alone > ethionamide.
i will like to know if he is presenting with any clinical symptoms like: nausea, vomiting, abdominal tenderness, discomfort near the ribs on the right
upper abdomen, jaundice (yellowing of skin and whites of the eyes)
Asymptomatic patients with an increase in LFTs from baseline:
a. if the increase in LFTs is
b. for asymptomatic patients, if the serum transaminases increases > 3-5x normal: hold INH until levels return to baseline.
i will like to know if your brother is presenting with any of this signs so i be more specific in my answer
hope u got something out of this