My mother in law suffers from cirrhosis of the liver, she s had a transjugular intrahepatic portsystemic shunt placed in her liver in early 2010 due to portal hypertension . She s Hep C positive and interferon treatments were unsuccessful, twice. Also in 2010 she had heart surgury on her main coronal artery with 85% blockage with subsequent plural effusion . She has diabetes mellitus 2. She s also on Xifaxin and 45mL of Lactulose 4 times a day. Her platelets are under 35k with reaccuring spontaneous bacterial peritonitis, hepatic encephelopathy and various other ailments. Her Meld score is currently 20. Overall, my question is this. After 3 weeks of elevated blood glucose levels which are consistently between 400-550 during any random and fasting readings, and trips to the ER 2 days consecutively, I feel that they are not sure exactly what s going on, but ever since this started 3 weekes ago after a severe UTI, a week stay in the hospital and an Albumin theraphy, I feel as if they are not telling us something. She s gone from 10 units of Novolin with great results over the past two years, to over 100 units daily of humilin R and lantus while her glucose is still skyrocketing. I ve also noticed signs of ketoacidosis, but that s from only internet research so I might be looking too far into it. Any thoughts are appreciated! Mike