Hi there ~ I understand your concerns for your husband and it is credible to believe that he has been trying his best to get rid of the excess weight. Unfortunately there are only two ways to gaining or losing weight - one being exercise, which will increase your appetite or help lose fat and the other being eating right, meaning to say eating more or less if you want to gain or lose weight. Thought there may be medicines that help in the process, the above mentioned are natural and do not have side effects. I hope you understand. Please consult a psychiatrist who can help with these issues. Take care and have a lovely day!