Dear Doctor, My grandmother aged 87 years is suffering from severe constipation for almost 10 days now. She was hospitalised around 10 days ago with asthmatic breathlessness and water retention. She was discharged after 6 days but has not passed her stools since the time she was hospitalised. She has tried enema twice while in hospital with no effect, dulcolax suppository with very little effect. Her doctor has advised dulcolax tablets but it has been of no help. She passes gas and urine regularly but no stools. Please advise if further suppository is safe or should we look at any other option. She is currently on medication Asomex, Sorbitrate, Defcort, Nebulizer ( Duolin ), Sizopin, sulpitac, zicam.