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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest A Treatment For Pulmonary Embolism And Lupus Anticoagulant Disorder

I am a 24 year old male, 5'9" and 175 lbs. recently had a pulmonary embolism and i am now taking coumadin daily and going to the local coumadin clinic to be monitored. i was also just diagnosed with lupus anticoagulant disorder. i smoke marijuana roughly 4 or 5 times a day. will this affect my coumadin or the disorder?
Mon, 25 Aug 2014
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Rheumatologist,  's  Response
Good evening sir. You have Antiphospholipid Syndrome( Lupus Anticoagulant antibody) is positive. IT is a disease where the blood clots at an increased frequency. I had suggest you to stop Marijuana as both Coumadin and Marjuana are metabolized in the liver and marijuana can affect the dose effect of coumadin. Also, it is a well known fact that smoking can accelerate any autoimmune problem.It increases the pace of the disease 5 times more and antiphospholipid syndrome being an autoimmune condition can get accelerated. SO i had recommend you to stop smoking . Hope the information was useful.
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Rheumatologist,  Dr. Bharat K Singh's  Response
Dear Friend,

thanks for sharing question.
You are having Antiphospholipid antibody syndrome and require life long anti coagulation. Concomitant use with marijuana may decrease warfarin metabolism or decrease the amount of warfarin bound to plasma proteins and increase warfarin effects, results in an increase in international normalized ratio and toxicity.
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Suggest A Treatment For Pulmonary Embolism And Lupus Anticoagulant Disorder

Good evening sir. You have Antiphospholipid Syndrome( Lupus Anticoagulant antibody) is positive. IT is a disease where the blood clots at an increased frequency. I had suggest you to stop Marijuana as both Coumadin and Marjuana are metabolized in the liver and marijuana can affect the dose effect of coumadin. Also, it is a well known fact that smoking can accelerate any autoimmune problem.It increases the pace of the disease 5 times more and antiphospholipid syndrome being an autoimmune condition can get accelerated. SO i had recommend you to stop smoking . Hope the information was useful.