Have taken generic Celexa for about 3 years, first 20 mg then 40 when 20 didn t seem to help. However, 40 taken consistently makes my brain feel totally flat. With my doctor s help, I ve tried a combination of 20 for a couple days, than one day of 40. That seemed to work for awhile. Now, I m trying 20 again. I think I need a change. I have a Dr. appt tomorrow, and will tell him I think I ve hit the wall with Celexa. Over the course of the past 18 years, I ve taken Zoloft, Wellbutrin, Lexapro, and Celexa. Zoloft and Wellbutrin worked well for some time, but eventually they began to have serious effects on the liver. Any suggestions on how best to talk to my internal med doc?