Is there an OTC laxative that is safe for me to use for chronic constipation, if I have kidney disease? I take several pain medications (for over five years) that have resulted in chronic constipation. My primary care physician recommended mineral oil, which I use once or twice a week. I have had two severe GI episodes in the past two months - one was diarrhea and the other was gas and vomiting. I can t see my PCP for two weeks and will not see my kidney specialist until October. I do not have the symptoms of an intestinal blockage - no bloating, no abdominal pain, and I had a BM yesterday. I thought this was going to be a simple question but none of my medical conditions is simple. Medical and Prescription Drug History: I have hypertension, chronic kidney disease and stage 3 kidney failure for which I take a 20Meq of potassium, DVT taking warfarin, severe cervical and lumbar osteoarthritis and other degenerative problems for which I take an opioid, Nucynta, plus Cymbalta, Limbrel, Zanaflex; I take Labatalol and Lasix for the hypertension - the Lasix causes problems with my kidneys but I retain fluid too much to stop taking it completely. I have had three surgeries on my cervical spine - two ADCF and one posterior cervical laminectomy and fusion with mass instrumentation. The only other surgery that I have had was an arthroscopic rotator cuff and labrum repair on my right shoulder. Might as well mention that I had a duodenal ulcer at the age of 15. I am a non-smoker, age 58; 6 0 tall; weigh 250 lbs and lived an active life until three years ago with the past year being very sedentary. Email: YYYY@YYYY