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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest An Effective Alternative Medication For Norethisterone

I have being taking a low dose of Norethisterone daily for 25 days, but it has exacerbated all of my pms symptoms, including headache, migraine, stomach upset,72 hour colds, constipation, mood swings, night flashes, poor sleep etc I have now stopped it. I am awaiting a hysterectomy due to fibroids but think I may be menopausal so am not sure this is the best solution. Is there an alternative to this medication?
Mon, 3 Mar 2025
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General & Family Physician,  's  Response
Hi,

There are other hormonal alternatives to Norethisterone such as Medroxyprogesterone, this would also reduce any bleeding you may be experiencing. Non hormonal alternatives are also available and may be a better option for you eg tranexamic acid, this can decrease bleeding by 30 to 55% in some women.

Additionally NSAIDs , taken the first 5 days of a menstrual cycle, can also decrease bleeding as well. These should be used with meals to minimize the effect on the stomach. You may want to consider speaking to your doctor to see if one if these options would better suit you.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Michelle Gibson, General & Family Physician
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Suggest An Effective Alternative Medication For Norethisterone

Hi, There are other hormonal alternatives to Norethisterone such as Medroxyprogesterone, this would also reduce any bleeding you may be experiencing. Non hormonal alternatives are also available and may be a better option for you eg tranexamic acid, this can decrease bleeding by 30 to 55% in some women. Additionally NSAIDs , taken the first 5 days of a menstrual cycle, can also decrease bleeding as well. These should be used with meals to minimize the effect on the stomach. You may want to consider speaking to your doctor to see if one if these options would better suit you. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Michelle Gibson, General & Family Physician