Hello I myself 36years old male,doing job as sales man at showroom,suffering from major depression and anxiety, after consulting psychiatrist i was on medicine zyven od 100 twice/day, mirtaz 7.5 thrice/day, vilazine 20 twice/day after increasing dosage and petril-0.5/sos, but result was nil then electroconvulsive therapy was given uptill 8 session just before 2 month and i was feeling better then before but as time started passing those symptoms returned back and doctor increased the dosage. Recently i m on this dosage:- lemez 100 twice/day, zyven od 100 twice/day, mirtaz 15 thrice/day, vilazine 20 thrice/day, rabicer-d once/day and petril-0.5 / sos. But still not feeling cured, still facing same problems like before:-blocked mind,lack of confidence,confusion,problem concentrating-remembering,short breath,fast heartbeats,problem communicating/talking with anybody,very slowed body movement thinking and decisions making too,need force from inside to speak then also sounds lower voice, feels like keep myself sited at corner far from everyone, feels better like 50% once in 7 to 10 days. My question is what can be the reason still not cured after all this treatment as when i don t have any kind of other tension personally or at my work place,is it possible either combination of medicine is not proper or is it over dosage, do i need consult another psychiatrist ? Thanks