For high BP, lifelong treatment is required with a combination of medicines to effectively control BP. Besides medicines, lifestyle changes are needed for sustained control of high BP. For control of blood pressure (BP), initially one drug is recommended. If one drug does not control BP effectively, then a combination of two, three, and four drugs depending upon control of BP, is recommended. You are taking the best combination – losartan and hydrochlorothiazide. Both of these drugs complement each other’s effect. Advice 1. Losartan HCTZ as suggested 2. Regular exercise at least 30 minutes for 5 days in a week. The best types of exercise for lowering BP are walking, jogging, cycling, swimming and dancing 3. Eating a diet that is rich in whole grains, fruits, vegetables and low-fat dairy products 4. Consume less salt 5. Avoid smoking, alcohol, coffee and caffeinated beverages 6. Lose extra weight if you are overweight 7. Measure your BP regularly and be in touch with your doctor 8. Investigations a. Blood sugar (fasting & post-prandial) b. Fasting lipid profile c. Serum creatinine If your BP is not getting controlled by above measures then you should take a second opinion from a cardiologist. I hope this information will help you. I will be happy if you ask another question Thank