Hi, dear I have gone through your question. I can understand your concern. Your IgE level is very high. It suggest some allergy or hypersensitivity. There are many causes of high IgE level. Allergy, asthma, hypersensitivity, parasitic infection and many other can lead to increase IgE level. You should check your complete blood count and go for allergy test once to search any allergens. Antihistaminic drugs and steroid are useful in these conditions but there are prescription based medicine so consult your doctor and take treatment accordingly. Hope I have answered your question. If you have any doubts then feel free to ask me. I will be happy to answer. Thanks for using health care magic. Wish you a very good health.