hi, thank-you for providing the brief history of your daughter. as you see and understand the anatomy of the ankle and the biochemics of the ankle you will notice that the muscles supporting the ankle joint are actually having origin in the leg bone that is the tibia and the fibula. Any injury occuring like sprain of ankle, fracture of ankle , crush injury of ankle, etc will straight away give pain in the muscles of the leg due to pull of the muscle. The muscles in the leg region will become fatigue and also will be in pain called as the referred pain. By a thorough clinical examination and x-ray or MRI we can understand the possible soft tissue Injury and also understand the pathomechanics of the joint and muscle. Treatment will be directed towards the drug therapy for pain relief and also physical therapy to regain the mobility in the ankle and flexibility of the muscle arising from the leg region. In my clinical practice we perform a thorough clinical examination and understand the pathomechanics, post which treatment is initiated and the results found are good. Regards Jay Indravadan Patel