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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Remedy For Prolonged Acid Reflux While On NSAIDs

I have been on Nsaids for the past 221 day due to 2 hips surgeries. I am having sever acid reflux. I ve had acid reflux and stomach trouble all my life but not like this. I have cramps high in my stomach on the left side and am regurgitating my food. I m currently on Prevacid and milanta. Should I be concerned that this is more serious than just heart burn?
Mon, 6 Jul 2015
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General & Family Physician,  's  Response
Hi & Welcome.

I appreciate your concern for the safety of NSAID on prolonged use.

NSAIDs induced acid reflux or injury to the lining of the food pipe or stomach is due to suppression of protective substance prostaglandin (the synthesis of which is inhibited by NSAIDs).

This can be minimized or prevented by use of:

1. PPI drug (to be taken one hr before meals)
2. H2 blocker (like Ranitidine)
3. Prostaglandin E1 analogue (Misoprostol).

Another preventive measure is by taking NSAIDs after having meals.

Hope to have answered your query.


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Suggest Remedy For Prolonged Acid Reflux While On NSAIDs

Hi & Welcome. I appreciate your concern for the safety of NSAID on prolonged use. NSAIDs induced acid reflux or injury to the lining of the food pipe or stomach is due to suppression of protective substance prostaglandin (the synthesis of which is inhibited by NSAIDs). This can be minimized or prevented by use of: 1. PPI drug (to be taken one hr before meals) 2. H2 blocker (like Ranitidine) 3. Prostaglandin E1 analogue (Misoprostol). Another preventive measure is by taking NSAIDs after having meals. Hope to have answered your query.