Hi welcome to HCM I have gone thru your query regarding high level of sedimentation rate I can understand your concern . Dear , I would like to know your age ,are a male or female ? . ESR is no doubt quite high . Normal rate should be 0-20 ,and 0-30 in above 50 elderly female and 0-15 and in above 50 elderly male 0 - 20 in male For your info , most of health problems are outcome of weak immunity due to our faulty life style and food habits . Modification by following regime , of regular exercise , walk , yoga ,pranayam , medtation for proper blood circulation & cleansing of body and mind and including intake of essential nutrients regularly ,helps strengthen immunity and gives resistance from diseases . High ESR levels can be outcome of inflammation of your arthritis and can be the side efect of its medication Prednisone . There are foods that can help to reduce inflammation . Balanced Diet rich in fibre , vitamins , minerals and antioxidants in natural form and antioxidants -ginger , garlic , fresh vegetables, fruits and flax seeds , blue-berries and cranberries , pineapple. Omega-3 fatty acids, found in the oil of fatty fish, & Olive oil contains a type of antioxidant can provide extra protection against inflammation . . , A spoon of Turmeric powder with a cup of hot milk +a spoon of Almond oil at ed time is a natural antibiotic , antioxidant , helps alley pain and inflammation . Lemon juice with warm water ,a pinch of salt and black pepper is an effective antioxidant and energiser . Avoid food that is high in saturated or trans-fats like fried , fast foods , refined sugars and fine floor prducts , tea , coffee , alcohol , sleeplessness , dehyderation , constipation . worry ,stress all induce toxins in your body . ,it is advisale to consult your doctor before following any regime Hope this helps solves your query .Take care , All the best . Don t hesitate to get back if have any further query