Hi,
Atrial
fibrillation (AF) is characterized by disorganized, rapid, and irregular atrial activation with loss of atrial contraction and with an irregular ventricular rate that is determined by AV nodal conduction.In lay-man'words your Atrium, i.e., small chambers of heart are beating rapidly and irregularly so that your ventricles or larger chambers are also beating rapidly & irregularly but conducting tissues between atrium and ventricle (atrio-ventricular node) can to some extent control the rate of ventricles beating by partly blocking conduction of electrical impulse.
Clinical consequences are related to rapid ventricular rates, loss of atrial contribution to ventricular filling, and predisposition to
thrombus formation in the
left atrial appendage with potential embolization.
Rate control of ventricles can be achieved with beta blockers like atenelol. The initial goal is a resting
heart rate of less than 80 beats/min that increases to less than 100 beats/min with light exertion, such as walking. Some patients who remain in AF chronically, develop tachycardia-induced
cardiomyopathy and consequent lung congestion.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Tushar Kanti Biswas,
Internal Medicine Specialist