Thanks for consulting me at HCM. I have carefully worked through your case, and can well realize your health worries. Being your physician, I want to assure, I will take care all of your medical concerns according to the latest medical guidelines. No there is no drug-drug interaction reported clinically for taking both of these drugs concomitantly. Nebivolol (Bystolic) is usually used as an antihypertensive agent, and amoxicillin for the infections. Both can be taken at the same time without any issues. Hope I answered all of your questions. Please click on I Find This Answer Helpful and don t forget to add your precious positive feedback to help me able to assist you better in future too. For any disease you have, a timely follow-up regarding the treatment efficacy and to see if there is any need to change the treatment options is very necessary. So keep a follow up to see how you doing. Remember to write down my name in the start of your question next time, & I will be with you right away. I am available 24/7 for providing you expert medical opinion on any health issue. Have a blessed time ahead. Regards! DR. MUHAMMAD HANIF USA