Hi Doctor, I developed hypothyroid 6 years ago, I was first diagnosed with borderline hypothyroid but not treated for two years when I was prescribed 25mg thyroxine and nothing further for another 12 months when I was prescribed 50mg thyroxine, today I am on 100mg thyroxine, but have not lost an ounce of the 2 and a half stone in weight I gained during the long dragged out treatment of my thyroid problem. neither has all the other symptoms associated with the condition abated, I would be obliged if you could offer some answers. thank you Margaret