Hi, The treatment for a distended gallbladder with calculi depends on the severity of the symptoms and the size and number of gallstones present. In your case, as per the report, a single 14.2 mm-sized mobile calculus is seen within the lumen of the gallbladder, and there is no pericholecystic fluid noted. As there is no pain or vomiting, it is possible that you are not experiencing any symptoms due to the presence of the gallstone. However, if you experience any symptoms like pain, nausea, or vomiting, then you may need to undergo treatment. The treatment options for a distended gallbladder with calculi include: * Medications: Certain medications can be prescribed to dissolve the gallstones or to reduce the symptoms associated with them. However, the effectiveness of these medications varies, and they may take a long time to work. * Surgery: Surgery may be needed to remove the gallstones and the gallbladder itself. The most common surgery used for this purpose is laparoscopic cholecystectomy, which involves making small incisions in the abdomen to remove the gallbladder. * Endoscopic retrograde cholangiopancreatography (ERCP): ERCP is a procedure that involves inserting an endoscope through the mouth and into the small intestine to remove the gallstones. It is important to discuss the treatment options with your doctor, who can recommend the best treatment based on the severity of your symptoms and the size and number of gallstones present. In addition, lifestyle changes like following a healthy diet and losing weight can help prevent the formation of gallstones. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician