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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Fatigue When Diagnosed With RA

Hi, I am 50 and was diagnosed with RA (RF and CCP pos) last year but believe I have had the disease for several years. I have no radiological damage and after 6 months of triple therapy wastried on Humira for 3 months and now Enbrel for the past 7 weeks. Both drugs worked well for a while and overall I feel there is only low level activity but I have had 2 short courses of low dose steroids. Over the last 3-4 weeks I have been having an increasingly severe local reaction with the Enbrel and 1-2 days of fatigue. It also does not seem to last more than 2-3 days and by the time my weekly 50 mg dose is due, I am quite miserable. I would like to know if a local reaction is associated with a decrease in efficacy and what I shoul do
Thu, 11 Dec 2014
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Rheumatologist,  's  Response
it seems that there is secondary resistance or failure of enbrel, so the options are to stop enbrel and maybe change over to a different biologic, like actemra or ristova.
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Suggest Treatment For Fatigue When Diagnosed With RA

it seems that there is secondary resistance or failure of enbrel, so the options are to stop enbrel and maybe change over to a different biologic, like actemra or ristova.