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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For High Cholesterol And SGPT Levels

Good Day,



I am having cholestrol and under statin,when i use this medicine my SGPT goes up and now it is 109.My concerns are

1.How can i controll both.

2.When i stoped statin for one month cholestrol rised to 312 and under medication for one month now it is 215.

3.Is this scenario is rare and any life threatening one,
Fri, 26 Jun 2015
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Cardiologist,  's  Response
Hello. I read your questions carefully.

In my experience, the liver enzymes should be raised three times above normal, in order to discontinue the statin. I would recommend you to consult your treating cardiologist to switch to another class of cholesterol-lowering agents (such as, bile acid binders, niacin). Although very rare, statins can cause dangerous complications such as rhabdomyolisis and myoglobinuria, let alone the elevation of liver enzymes, a complication found on 5-8% of people using them.

I hope I was helpful. Good day
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Suggest Treatment For High Cholesterol And SGPT Levels

Hello. I read your questions carefully. In my experience, the liver enzymes should be raised three times above normal, in order to discontinue the statin. I would recommend you to consult your treating cardiologist to switch to another class of cholesterol-lowering agents (such as, bile acid binders, niacin). Although very rare, statins can cause dangerous complications such as rhabdomyolisis and myoglobinuria, let alone the elevation of liver enzymes, a complication found on 5-8% of people using them. I hope I was helpful. Good day